Treatment outcomes of IMEP as a front-line chemotherapy for patients with peripheral T-cell lymphomas
نویسندگان
چکیده
منابع مشابه
Treatment outcomes of IMEP as a front-line chemotherapy for patients with peripheral T-cell lymphomas
BACKGROUND This study aimed to assess the treatment outcomes of ifosphamide, mesna, etoposide, and prednisolone (IMEP) combination regimen as a front-line chemotherapy in patients with peripheral T-cell lymphomas (PTCLs). METHODS Clinical data of 38 newly diagnosed PTCLs patients who underwent IMEP at Busan Paik Hospital from January 2002 to December 2013 were retrospectively analyzed. RESU...
متن کاملThe role of front-line anthracycline-containing chemotherapy regimens in peripheral T-cell lymphomas
Peripheral T-cell lymphomas (PTCLs) are a heterogenous group of aggressive non-Hodgkin's lymphomas that are incurable in the majority of patients with current therapies. Outcomes associated with anthracycline-based therapies are suboptimal, but remain the standard of care for most patients, even though the benefits of this approach remain uncertain. This study retrospectively examined outcomes ...
متن کاملImmunophenotyping of Nodal Peripheral T-cell Lymphomas and its Association with Epstein-Barr Virus
Background: Immunophenotyping in the rare group of nodal Peripheral T-cell Lymphomas (PTCL) exposes interesting features such as T-cell marker downregulation and paradoxically, the presence of reactive, clustered large-sized CD20 positive B-cells (B-cell proliferation). Epstein-Barr virus (EBV) has been suggested as a putative etiology in pathogenesis of B-cell lymphoma. We aimed to review the ...
متن کاملTreatment outcomes of dose-attenuated CHOP chemotherapy in elderly patients with peripheral T cell lymphoma
Background While cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) is the most commonly used chemotherapeutic regimen for patients with peripheral T-cell lymphomas (PTCLs), elderly patients are more vulnerable to associated toxicities. We evaluated the efficacy and safety of dose-attenuated CHOP in elderly patients with PTCL. Methods Patients with PTCL aged >70 years or 65-7...
متن کاملPeripheral T-cell lymphomas.
The development of T cells from stem (progenitor) cells to effector cells results from a two-wave process of proliferation and differentiation. The cells of the first differentiation wave are the precursor T cells, and those of the second differentiation wave are peripheral T cells. In the first differentiation wave, resting/circulating naive antigen-reactive T lymphocytes are produced which di...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood Research
سال: 2016
ISSN: 2287-979X,2288-0011
DOI: 10.5045/br.2016.51.3.187